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found that pathogenetic variants in LIG3 cause mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)-like syndromes with CIPO [33]

doi: 10.1523/JNEUROSCI.2083-19.2020, 119 KuoY

Blood 91 , 706709 (1998)

Recent cryo-electron microscopy studies have further revealed a conserved -syn filament architecture shared among PD, Parkinsons disease dementia (PDD), and dementia with Lewy bodies (DLB), which is distinct from the filament structures observed in multiple system atrophy (MSA) (Schweighauser et al., 2020)