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By improving oxygen unloading, ITPP reduces tissue hypoxia and tempers the overactivation of hypoxia-sensitive signaling

Therefore, when cells need more energy to function, mitochondrial respiration is stimulated to supply more ATP 51

Abbring, Suzanne, Daniel Kusche, Thomas C

Semen cryopreservation, drug treatments, and experimental group settings Before semen cryopreservation, six semen samples were individually split into 4 equals and diluted to a final concentration of 6.0 10 7 /ml spermatozoa with the basic extender supplemented with 0 g/ml SeNPs and 0 mM GSH (negative control group, NC), 2 g/ml SeNPs (SeNPs group) (27), 4 mM GSH (GSH group) (50) and 4 mM GSH plus 2 g/ml SeNPs (GSH + SeNPs group)

A major issue is the emergence of drug resistance resulting from prolonged usage of these medications