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Description

Identification of the Lipolytic Domain of GH Pre-clinical studies identifying the C-terminal region of GH as the locus of its lipolytic activity established that peptides corresponding to positions of hGH retained significant fat-mobilising activity in adipocyte models and in vivo, while lacking the growth-promoting and insulin-antagonistic effects of full-length GH

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Growth hormone fragment signaling: In vitro work on downstream pathways modulated by the 176-191 fragment compared with full-length GH, including cAMP and MAPK-related cascades