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Treatment with intra-tracheal administration of NAC on pulmonary edema formation induced by phosgene exposure in rabbit lungs lowered pulmonary artery pressure, lung weight gain, the concentration of peptide leukotrienes LTC 4 , D 4 , and E 4 , and lipid peroxidation which were increased following exposure to phosgene (84)

(5322:) Ribose-phosphate pyrophosphokinase I (Phosphoribosyl pyrophosphatesynthetase I) (PRS-I) (PPRibP)

Loading of RAW264.7 cells with oxidized low-density lipoprotein followed by LPS stimulation elevated GSR expression, and this correlated with a more rapid drop in cytosolic and mitochondrial NADPH in our assay

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2 , 3 Additionally, cancer cells are prone to develop resistance to chemotherapeutic drugs resulting from drug inactivation or efflux, target protein alteration, DNA damage repair, and signaling cascade alteration, which greatly limits the efficacy of such drugs