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One particularly outstanding function is the transformation of harmful substances in the body

Increased HSPs can reduce inflammatory responses to improve tolerance to heat stress and prevent intestinal epithelial damage [32]

95 Gene deletion or the lack of unstable methyl groups in the form of methionine and choline undermines the ability to synthesize SAM, which leads to the development of steatosis and its rapid progress toward NASH

xCT-overexpressing cancer cells depend on glucose, glutamine, and fatty acids for an energy source to acquire proliferative and survival advantages [16,17,19,68]

Preclinical and Clinical Studies with Antioxidants Although evidence of oxidative damage in ALS pathogenesis has been largely described in the literature, all antioxidants tested in patients have so far failed, remaining unclear whether any antioxidant therapies might be effective for treating ALS