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In early-onset schizophrenia cases, methylation dysregulation of MB-COMT and 5-HT2A was partially corrected by antipsychotic treatment, and hypermethylation of 5-HT2A in the prefrontal cortex was correlated with treatment response (Abdolmaleky et al., 2006

Neuronal GPX4 is downregulated after SCI, and ferroptosis inhibitors SRS 16-86 and DFO both prevent the reduction of GPX4 and improve the survival rate of neurons in the injured spinal cord to repair SCI-associated motor dysfunction

Hu B, Zou X, Yu Y, Jiang Y, Xu H

In contrast, insulin acts as a negative regulator, inhibiting its synthesis

All raw reads are archived in the National Center for Biotechnology Information Short Read Archive (SRA) under BioProject number PRJNA746598, transcriptome assembly and annotation files are available at and scripts for read processing, transcriptome assembly, and holobiont parsing, are available at Average sample mapping efficiency to the concatenated host and symbiont transcriptomes was 48%, with higher mapped reads to O