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The anticancer effects of ISA involve proliferation inhibition, ROS overproduction, apoptosis induction and cell cycle arrest

The expression level of pyruvate dehydrogenase (encoding by aceE ), which catalyzes the reaction from pyruvate to the formation of acetyl-CoA, was only 0.13-fold in MG12345

J Cell Sci 121(Pt 14):23082318

(b) Heatmap and hierarchical clustering of the Pearson correlation matrix for all assays based on the DNA methylation measurements for regions 07 and 08 (for which two replicates of clonal bisulfite measurements were available) in the tumor/normal samples

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