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To illustrate this point, lets consider the human oncogenic fusion protein BCR-ABL

Funding LM is supported by UNAM-PAPIIT IN202922 and CONACYT A1-S-17357 grants and LG-V is supported by DGAPA-UNAM postdoctoral fellowship

Oral berberine ameliorates high-fat diet-induced obesity by activating TAS2Rs in tuft and endocrine cells in the gut

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In this review, we discuss synthetic approaches to ALA and R -ALA over the past 70 years (1952 to the present), which will help medicinal chemists further develop novel routes for their synthesis