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Together, these observations strongly support the proposed role of iNOS and NO in mediating erastin-induced ferroptotic cell death in cultured hepatocytes

Of special relevance to our study, RNR consumes reducing equivalents supplied by GSH, as well as thioredoxin, in mammalian cells (Zahedi Avval & Holmgren, 2009

Electron transport through the complexes is coupled to proton translocation via the mitochondrial inter membrane space, forming an electrochemical proton gradient (electromotive force) and a mitochondrial transmembrane potential ( m ), necessary for generation of ATP

Expert Opinion refers to a statement, achieved by consensus of the Panel, that is based on Panel members clinical training, experience, knowledge, and judgment for which there is no evidence

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