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Poggio M, Hu T, Pai C-C, Chu B, Belair CD, Chang A et al

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In in-vitro research, the GHK peptide (copper tripeptide-1) has been characterized as a modulator of multiple cellular pathways relevant to skin regeneration

In summary, it is not difficult to find that continuous ER stress can accumulate necessary material conditions for the occurrence of ferroptosis such as ROS and Fe 2+ through UPR and can enhance the sensitivity of cells to ferroptosis by the increased expression of IRE1 in the process of JEV and HSV infections

Despite encouraging preclinical and early clinical results, several critical gaps must be addressed before MSC- and MSC-derived exosome-based therapies for diabetic complications can be developed