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Although considerable progress has been made in elucidating the interaction between oxidative stress and ERS in AKI has been established, further in-depth studies on their precise mechanisms are needed

Malle EK, Zammit NW, Walters SN, et al

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These dual roles highlight the metabolic and immunologic plasticity of tryptophan in pulmonary fibrosis and suggest that selective modulation of its downstream pathways may offer promising antifibrotic strategies