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Some ionophores can increase NO levels and reduce pro-inflammatory cytokine levels, indicating their anti-inflammatory potential [234]

Sep 2023;51(9):400-407

Chromatin remodeling factors, such as HELLS, suppress ferroptosis by altering the expression of lipid metabolism genes like SCD and FADS2, which regulate monounsaturated fatty acid (MUFA) synthesis to counteract lipid peroxidation [81,82,83]