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The role of HSPs in NDDs HSPs play a dual and indispensable role in NDDS: they either facilitate the correct folding and stabilization of misfolded proteins or target irreversibly damaged proteins for degradation via autophagy or UPS

55 This was not a region that Pirh2 reportedly bound to on p53 (Figure 1), suggesting that p28 did not directly block the binding of Pirh2 on p73 and alter its ubiquitination

This upregulation enhances the tissues capacity for lipolysis and fat oxidation

GRADE-assessed systematic review and meta-analysis of clinical trials

Each semen sample was prepared in the standard fashion using a Percoll gradient and final pellet resuspension in 0.5mL of fresh medium