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(2020) 105:e213444

Metabolic interactions in cancer: Cellular metabolism at the interface between the microenvironment, the cancer cell phenotype and the epigenetic landscape

10.3389/fbioe.2023.1205751 46 MaB.XuH.ZhuangW.WangY.LiG.WangY

Two IGF-I analogs that bind poorly to IGF-binding proteins, the truncated form, des(1-3)IGF-I, and a variant with an N-terminal extension as well as arginine at residue 3, LR3IGF-I, were approx

Moreover, LBP was shown to improve the quality and quantity of pancreatic -cells, promoting insulin secretion via multiple protective mechanisms, thus alleviating DM (Figure 3)