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Description

The gut microbiota and its implication in the development of atherosclerosis and related cardiovascular diseases

Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism (Mari et al., 2013)

V.KantR.SajjanarB.et al

By preventing this damage, glutathione preserves cellular NAD+ pools

R -ALA was synthesized through the resolution of racemic ALA by enzymatic esterification of the carboxylic group, which consists of four carbon atoms away from the stereogenic center (Scheme 21)