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10.1001/jamanetworkopen.2020.24335 132 ShadkamiF.JonesA

For example, depleting TF from serum or using RNA interference (RNAi) to downregulate TfR significantly inhibits ferroptosis in mouse embryonic fibroblasts (Gao et al., 2015)

Blood-Brain Barrier Permeability Structural Advantage: Unlike many peptides that struggle to penetrate the blood-brain barrier, it's small molecular size and lipid solubility allow it to cross easily