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Cardioprotective potential of transcription factor PRRX1 silencing against myocardial ischemia/reperfusion injury by regulating excessive mitophagy and ferroptosis through FKBP5-p38 MAPK axis

these include increased metabolic flexibility, uptake of extracellular amino acids via compensatory transporters and macropinocytosis, and expression of nutrient stress-response proteins (Fig

This indicates that GAD67 is not only involved in maintaining metabolic levels of cellular GABA but may also contribute to the rapid vesicular accumulation of GABA in the presynaptic terminal for covering the incremental needs of synaptic neurotransmission by vesicular release into the synaptic cleft (Kanaani et al., 2010)

J Clin Invest (2011) 121(6):24226.10.1172/JCI45027 262 VijayakumarAWuYSunHLiXJeddyZLiuCet alTargeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration

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