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doi: 10.1021/es404159k 56

If this is a concern, timing your injection for the evening before a day when you have flexible access to a restroom is a sensible precaution

A 2026 systematic review confirmed that L-Citrulline, especially when combined with antioxidants, increases nitric oxide bioavailability and reduces oxidative stress in endothelial cells

The authors noted that the synergistic effect of rifaximin and probiotics might enhance efficacy, but long-term follow-up and mechanistic studies are still needed for further validation

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