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TREM2 maintains microglial metabolic fitness in Alzheimer's disease

Damage-released DNA fragments activate the cGAS-STING pathway, converting genomic instability into antitumor immune responses, and the circadian protein neuronal PAS domain protein 2 enhances HR repair by stabilizing H2AX mRNA, suggesting circadian regulation of repair efficiency (67-69)

Under HS, massive intestinal epithelium loss occurs, which increases intestinal permeability and bacterial translocation

L.Benjamin-DavalosS.KorolevaM.MacfarlandD.MindermanH.et al (2021)

Liu and colleagues found that pectin from comfrey roots could lessen colon damage from DSS in rats and repair the intestinal barrier (110)