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Ann N Y Acad Sci 1201:96103

Traumatic brain injury induces elevation of Co in the human brain

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For example, deficiencies in vitamins B6, B12, and folate can impair methylation processes, as these vitamins are required for the production of SAMe, a key methyl donor

It increases VEGF receptor activity to promote new blood vessel formation, enhances collagen synthesis and organization, activates the ERK1/2 signaling pathway for cell proliferation and migration, and modulates inflammatory responses to optimize healing conditions