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nitric oxide for example the substrate for formation of nitric oxide, the amino acid arginine, the stability of nitric oxide in the blood, or the effect of nitric oxide drugs which act on differing systems such as the central nervous system and peripheral vascular system, may also be used synergistically

5 Gut microbiota and metabolites targeted interventions against CKD progression in the gut-brain-kidney axis Gut dysbiosis is implicated in the progression of a range of diseases, including cardiovascular disease, type 2 diabetes, neurodegenerative conditions, and CKD, among others, via mechanisms that are yet to be completely understood

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Glucagon is a hormone involved in glucose control