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Typically that's done at night before sleep for the reasons that we talked about before

Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin. The Lancet , 2021

In most cases, any side effects are gone within a few days to a week

Coggins, PharmD, CGP, FASCP, is senior director of pharmacy services for skilled nursing centers operated by Diversicare in nine states, and is a director on the board of the American Society of Consultant Pharmacists