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02/06 FDA rev date: 9/15/2006 Side Effects for Nascobal The incidence of adverse experiences described in the Table below are based on data from a short-term clinical trial in vitamin B 12 deficient patients in hematologic remission receiving Nascobal (Cyanocobalamin, USP) Gel for Intranasal Administration (N=24) and intramuscular vitamin B 12 (N=25)

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421 Specifically, dysfunction within the ventrolateral periaqueductal gray (vlPAG)-mediated descending pain modulatory system has been reported in patients with PDPN

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