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doi: 10.1186/s13195-018-0451-2 68 WandersR

A correlation between severe reduction of GSH levels and PD onset was recently proposed 50

The standard concentrations were in the range of 5002500 mol l 1 for amino acids, and in the range of 7.6152 mol l 1 for acyl-carnitines

Checkpoint blockade antibodies against CTLA-4, PD-1, and PD-L1, can restore glucose in tumor microenvironment, permitting T cell glycolysis and IFN- production, and blocking PD-L1 directly on tumors dampens glycolysis by inhibiting mTOR activity and decreasing expression of glycolysis enzymes (270)