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White Metallomics Research by Clare Duncan et al., published in Metallomics

a recent study showed that more than one-fourth of undiagnosed subjects had evidence of likely or definitive monogenic disorder as the cause of or significant contributor to their liver dysfunction using WES [80]

This segment starts at 14:55

This could help answering whether glutamate in the GLAST KO model was indeed the rate-limiting substrate from GSH synthesis or if neurodegeneration was mainly due to glutamate neurotoxicity