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Studies have examined its influence on more than 4,000 human genes and its role in collagen and elastin synthesis and the skin's natural renewal processes

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It's a less severe concern than, say, copper toxicity, but it's a practical safety issue that must be considered

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Notably, histological analyses revealed that SYNCRIP expression was enriched in GBM tissues compared with lower-grade gliomas and normal brain tissues, suggesting a GBM-specific oncogenic role for SYNCRIP in tumor progression (Figure 1A-B)