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PET tracers targeting transferrin receptors underperform in diffuse axonal injury, as injury boundaries are unclear and non-specific uptake occurs in perihematomal edema, resulting in signal levels below clinical detection thresholds

Extensive research underscores the superior stability of organic trace elements in the animal gut, their reduced susceptibility to degradation, and fewer antagonistic interactions with other compounds

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Interestingly, a weaker cortisol awakening response is observed in patients with depression, mania and partial remission against those of healthy control subjects (260), thereby indicating dysregulation of HPA axis in bipolar disorder subjects

doi: 10.1080/10408398.2020.1854675 191 YeohY