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111 A study conducted by Fernandez et al revealed a notable inhibitory effect of rapamycin on T cell activation in individuals diagnosed with systemic lupus erythematosus (SLE)

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Reported Side Effects: Injection site reactions (most common) Headache Mild water retention Transient dizziness Fatigue (temporary) Joint stiffness (with GH elevation) Rare/Serious (requiring immediate attention): Significant swelling of hands, feet, or face Chest pain or shortness of breath Vision changes Allergic reactions FDA Concerns: Immunogenicity risk Limited clinical safety data Classified as Category 2 bulk drug substance presenting significant safety risks Regulatory Status United States: Not FDA approved for any indication

The femoral head and the acetabulum are wrapped by a piece of cartilage called the labrum