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& Deppmann, C

This action is likely related to SINs ability to enhance IB protein expression, effectively inhibiting NF-B signaling and regulating micro-glial inflammation (4, 95, 96)

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Cells amplified via epithelioids can also be used to generate organoid cultures with a similar efficiency to tissue (Extended Data Fig

The Weapons: Cytokines and Chemical Mediators All cells involved in inflammatory responses communicate with one another via abundant and complex signals that have multiple and sometimes apparently conflicting roles in regulating what is potentially a highly destructive process