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D eNOS Endothelial nitric oxide synthase ERK Extracellular signal-regulated kinase FA Fatty acyl groups FasL Factor-related apoptosis ligand FoxO1 Forkhead box transcription factor O1 GLP-1R Glucagon-like peptide 1 receptor GP Glycerophospholipids GR Glutathione reductase GSH Glutathione HID 2-Hydroxyisoflavanone dehydratase HO-1 Heme oxygenase-1 HPA Hypothalamicpituitaryadrenal IBS-D Irritable bowel syndrome IGE Immunoglobulin E IGF Insulin-like growth factor IgM Immunoglobulin IL Interleukin JNK c-Jun N-terminal kinase Keap1 Kelch-like ECH-associated protein 1 LKB1 Liver kinase B1 LPS Lipopolysaccharide LTC4 Leukotriene C4 M3 Muscarinic receptor-3 MAO Monoamine oxidase MCP Monocyte chemotactic protein MDA Malondialdehyde MMP Matrix metalloproteinase MMP-9 Matrix metalloprotein-9 mTOR Mammalian target of rapamycin

Papanas N et al (2014) Efficacy of alpha-lipoic acid in diabetic neuropathy

[72] demonstrated that EP300 expression is significantly upregulated in hypoxic pulmonary vascular cells