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and (3) organ-level outcomes, such as cardiovascular, neurological, and digestive health, as well as hormonal regulation involving growth hormone (GH), cortisol, insulin, leptin, ghrelin, testosterone, and thyroid hormones

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Baseline gut microbiota and metabolome can modulate the durability of immunity to the SARS-CoV-2 vaccine to overcome waning immune responses over time and potentially predict immunogenicity to vaccines for up to 6 months (Peng et al., 2023)

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The vast majority of the published research is preclinical