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and the salt of 3,4-epoxybutyric acid of said formula (4) undergoes a nucleophilic substitution by trimethylamine, wherein R is chosen from alkylsulfonyl groups, arylsulfonyl groups, acyl groups, and phosphoryl groups, and M is determined by the salt used herein

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The concentration of all HDL particles in plasma is approximately 20 umol/L

Furthermore, we note Y211C/H are variants associated with SPCDchanges that likely causes large structural perturbation of the carnitine-binding site beyond simply affecting solvent structure

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