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Papenfort, K

A recent study revealed that TDP-43 accumulation within stress granules, together with oxidative stress, collectively induces intra-condensate demixing, leading to a TDP-43-enriched phase that forms pathological cytoplasmic aggregates (Yan et al., 2025)

The peptide preserves mitochondrial integrity by protecting against superoxide radical accumulation in mitochondrial compartments, maintaining efficient energy production and preventing mitochondrial-derived oxidative stress

The ZBP1-MLKL necroptotic pathway, through its interaction with tumor cell-intrinsic STING signaling, has been shown to drive persistent inflammation and enhance radiation-induced antitumor immunity (Yang et al., 2021)

Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for Homer 1b/c