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Since there is no response to hormonal therapy or HER2-targeted drug therapies, chemotherapy remains one of the main treatment options, yet the prognosis remains poor due to high recurrence rates and drug resistance (Won and Spruck 2020, An et al

Studies suggest that the R-form is absorbed more efficiently and is more biologically active

For superficial BCC that is not suitable for surgery or other treatments, imiquimod can be used, while 5-fluorouracil (5-FU) is used for SCC treatment

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Governed by specific writers, erasers and readers, these regulatory nodes are fundamental for understanding the lactylation landscape