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Macrogenomic analyses of various CVD patient populations have demonstrated significant differences in GM composition in the presence or absence of CVD and HF (170, 171)

Since there are known APOE -dependent differences in the gut microbiota in both humans and APOE-TR mice (Tran et al., 2019), L-carnitine metabolism could be impacted and, in turn, affect cerebrovascular function by disturbing normal L-carnitine shuttle function, particularly if other vulnerabilities are present

Bibcode:2022Natur.608..199H

In animal studies, L-carnitine was suggested to have a role in the prevention of age-related muscle protein degradation

Selain itu, suplemen L-carnitine juga dapat berinteraksi dengan obat-obatan tertentu