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Other studies reported that TMAO increased the expression of CD36 and the formation of foam cells induced by ox-LDL, which could be reduced by siRNA-mediated knockdown of CD36 as well as inhibitors of MAPK (SB230580) and JNK (SP600125)

Liu et al., 2021)

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Indeed, plasma choline was positively associated with a number of cardiovascular risk factors, such as BMI, percentage body fat, waist circumference, and serum triglycerides, and inversely associated with HDL-cholesterol

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