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Some assay formats also carry risk of misleading readouts when compounds interact with reporters, dyes, membranes, plastics, or plate surfaces, creating signals that appear pathway related but are driven by assay chemistry

Preclinical studies have shown that trazodone selectively inhibits neuronal reuptake of serotonin (Ki = 367 nM) and acts as an antagonist at 5-HT 2A(Ki = 35.6 nM) serotonin receptors

Comparison of attachment styles in borderline personality disorder and obsessive-compulsive personality disorder

H2-blockers