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In vascular dementia (VD) rats, SZJNF improved neuronal morphology, reduced synaptic dysfunction, and attenuated oxidative stress and apoptosis via calcium signaling pathways, highlighting its potential in treating AD-related neurodegeneration (Tian et al., 2021)

Some individuals use this combination with the aim of supporting physical performance or weight management, though clinical evidence supporting such benefits remains limited

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The mean follow-up was 38.25 months

When B12 levels are low, fatigue, weakness, poor focus, and low mood can become more noticeable