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High doses are primarily necessary in cases of proven deficiency, for example in: - Impaired nutrient absorption in the intestine (e.g., after surgery/in case of stomach problems) - Strict vegan diet with confirmed B12 deficiency - Chronic inflammatory bowel diseases - Elderly people with age-related absorption disorders If you belong to one of these groups, you should consult your doctor to choose the correct dose and method of administration

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14 These widespread benefits stem from GH and IGF-1's systemic effects, leading to variable individual responses

It effectively puts a roadblock on the pathway that stores new fat

Financial support and sponsorship Supported in part by NIH grant R01 AG057381