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Loss of MCUR1 or MCU activity has also been linked to reduced muscle mass and strength in mouse models, and MCUR1 was found to be downregulated on the mRNA level in older sarcopenic patients, suggesting that both proteins have a role in muscle regeneration [17, 28, 29]

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J Appl Physiol 102:10651070 Stumvoll M, Mitrakou A, Pimenta W, Jenssen T, Yki-Jarvinen H, Van HT, Renn W, Gerich J (2000) Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity