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10.1371/journal.pone.0025935 146 NogueiraN

Statin Statins are also a useful drug to lower testosterone in PCOS

93 Thus, further elucidating how neurofibromin modulates oestrogen signalling and vice versa might shed light on the role of sex hormones in regulating tumour growth in NF1 patients, and ultimately provide a rationale for repurposing agents that target oestrogen in order to inhibit neurofibroma development