Li X, Chen W, Zhang L et al (2013) Inhibition of store-operated calcium entry attenuates MPP(+)-induced oxidative stress via preservation of mitochondrial function in PC12 cells: involvement of Homer1a
Type 2 diabetes, in particular, has seen a continuous increase in prevalence, driven by lifestyle shifts and population aging, especially in Westernized societies, where these factors contribute to rising obesity rates
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GSH, an important intracellular antioxidant and hepatic detoxifier, is comprised of glutamic acid, cysteine and glycine.[3,4] Glutamine is one of the most important substrates for ammoniagenesis in the gut and the kidney due to its important role in the regulation of acidbase homeostasis.[5] It decomposes readily to yield ammonia and glutamate or via intramolecular catalysis to pyroglutamate
Besides, we demonstrated the shared mechanistic connections between chronic ethanol exposure and AD: oxidative stress and neuroinflammation, proved that chronic ethanol exposure may accelerate AD pathology by increasing A aggregation in mice and causing oxidative stress and neuroinflammatory impairments
