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Description

Nausea (feeling sick), vomiting (being sick): Take your methotrexate with food or in the evening

Adults:Take 1 capsule a day with meals or as directed by your health care practitioner

[DOI] [PubMed] [Google Scholar] Montanez R., Rodriguez-Caso C., Sanchez-Jimenez F., Medina M

I personally take them at night, otherwise Im too relaxed but this most probably depends on each body

Renal impairment may lead to increased exposure of concomitant medications and/or their metabolites that are primarily renally excreted [see Drug Interactions (7.4)]