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Dialogues Clin Neurosci 15, 445454

BPC-157 therapy regarding opioid substances Opioid drugs Opioids are used in pain treatment and belong to one of the main groups in this therapy

The protein Co-SMAD (SMAD4), which contains a nuclear localization sequence, binds to the phosphorylated SMAD2/3 dimer, allowing it to translocate into the nucleus