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In conclusion, by understanding the role of glutathione and making informed choices, we can enhance our health and well-being as we age

At the methodological level, isotope tracing technologies can directly resolve actual metabolic flux changes, single-cell and spatial multi-omics can help identify cell-cell interactions and substrate competition in the tissue microenvironment, and genome-scale metabolic modeling can be used for priority ranking and assessment of targetability

A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway

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The peaks for pyruvate and lactate were obtained using GC