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In addition, in the mitochondria, it is a cofactor of methylmalonyl-CoA mutase, the enzyme that catalyses the reversible isomerization of methylmalonyl-CoA to succinyl-CoA, an essential intermediate in the citric acid cycle (TCA, Krebs cycle)

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In each instance the total number of spines was counted for the treatment groups, control, Nlel-AnglV and Dihexa, to ensure an active phenotype

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Neurodegenerative diseases GST polymorphisms have also been associated with neurodegenerative conditions including Alzhaimer and Parkinson diseases (Table 1) 46,47