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However, hyperuricemia plays a role in promoting inflammation, oxidative stress, and endothelial dysfunction underscores its potential contribution to disease pathogenesis

Importantly, N -acetyl cysteine (NAC) and vitamin C lowered DSBs by 43 and 25% respectively, which was significantly more than any of the other agents studied [9]

Experimental antioxidant biotherapy for protection of the vascular wall by modified forms of superoxide dismutase and catalase

Prolonged exposure to hypoxia has been shown to induce pulmonary vasoconstriction and pulmonary arterial hypertension, which subsequently results in a sustained elevation of right ventricular afterload, thereby imposing formidable challenges on the structural and functional integrity of the cardiovascular system (3, 4)

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