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A typical protocol looks like this: Initial loading (for severe deficiency or pernicious anemia): Daily or every-other-day injections for 1 to 2 weeks, then weekly for 4 weeks Maintenance (pernicious anemia, ongoing absorption issues): Monthly injections indefinitely General wellness or dietary deficiency: Once every 1 to 3 months, depending on levels Your provider will check your B12 blood levels and recommend the right schedule for you

The affinity of S100A7 for calcium is higher than that for zinc (70)

Improved Mood: Helps regulate neurotransmitters that influence mood and mental clarity

the studies cited below are phase 1b and phase 2 trials

Science 336 , 12681273 (2012)