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We find that high Li exposure, ferroptosis, and unexplained miscarriage are closely associated and causally regulated, which is dependent on non-canonical MBOAT1 but not classical GPX4

As described in the Risk Factors section, smoking impairs fertility and leads to worse outcomes with assisted reproductive techniques

49 On the other hand, a population-based cross-sectional study including 21,148 Korean adults showed that participants with the highest intake of vitamin A, beta-carotene, and vitamin C had a significantly higher forced expiratory volume in 1 second (FEV 1 ) than those with the lowest intake

Notably, treatment with APR-017 alone affected neither ROS level nor cell viability, while treatment with IC261 alone slightly elevated ROS level and reduced cell viability