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To examine key transition points in evolution of virulence and host adaptation in the dimorphic fungi, we increased the phylogenetic density within the Ajellomycetaceae by sequencing the genomes of non-pathogenic and emerging species and then performed comparative genomic analyses of the systemic, opportunistic, and non-pathogenic species

However, If diarrhea and vomiting are experienced for a prolonged period of time, they can lead to variable degrees of dehydration, which can be life-threatening if not adequately addressed

4.5 Mn transporters in neurons and glia Identifying transporters of Mn in neurons and glia is important, as these cells regulate brain Mn homeostasis and are primary targets of Mn neurotoxicity (Pajarillo et al., 2021)

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Understanding the involvement of these enzymes in disease processes opens up opportunities for developing potential therapeutic targets